Necroptosis, which is a regulated form of necrosis, is the process of cellular self-destruction that is activated when apoptosis is otherwise prevented.
Pathway Description: Necrosis has been classically defined as an unprogrammed form of cell death that occurs in response to overwhelming chemical or physical ...
由 J Lou 著作 · 2021 · 被引用 26 次 — Regulated necrosis is an emerging type of cell death independent of caspase. Recently, with increasing findings of regulated necrosis in the field of bioc.
由 ML Escobar 著作 · 2015 · 被引用 28 次 — The necrosis process takes place in the absence of phagocytosis, and its final phase is characterized by the loss of the integrity of the cellular membrane. The ...
由 TV Berghe 著作 · 2014 · 被引用 1872 次 — This section describes the molecular events that initiate emerging pathways of regulated necrosis, including ferroptosis, oxytosis, ETosis, ...
由 DR Green 著作 · 2015 · 被引用 1151 次 — Necrotic cell death is characterized by the rapid loss of plasma membrane integrity. This form of cell death can result from active signaling pathways, the best ...
由 J Belizário 著作 · 2015 · 被引用 106 次 — Under stress conditions, cells in living tissue die by apoptosis or necrosis depending on the activation of the key molecules within a dying cell that ...
Necrosis is a form a premature cell death that, unlike apoptosis, is not programmed or regulated. This form of cell death most often occurs from conditions in ...
由 N Kim-Campbell 著作 · 2019 · 被引用 21 次 — Emerging pathways of specialized forms of regulated necrosis include cyclophilin D (CYPD)–mediated regulated necrosis involving the opening of the mitochondria ...