由 Y Itoh 著作 · 2015 · 被引用 397 次 — MT1-MMP is one of the most extensively investigated enzymes in the MMP family. It was originally discovered and characterized as a cell surface proMMP-2 ...
由 XD Xia 著作 · 2021 · 被引用 11 次 — Hepatic MT1-MMP promotes LDLR shedding, increasing plasma cholesterol levels and the development of atherosclerosis. On the other hand, macrophage MT1-MMP ...
由 Y Itoh 著作 · 2004 · 被引用 100 次 — MT1-MMP has been implicated in various physiological and pathological processes such as wound healing, bone development, angiogenesis, inflammation, rheumatoid ...
由 MA Cepeda 著作 · 2016 · 被引用 46 次 — Excessive ECM degradation mediated by high levels of MT1-MMP is not permissive to cell migration and tumourigenesis, while low levels of MT1-MMP ...
由 H OHKAWARA 著作 · 2015 · 被引用 9 次 — MT1-MMP is a signaling molecule of vascular proatherogenic changes induced by several proinflammatory and proatherogenic stimuli, which linked to impaired ...
由 Y Itoh 著作 · 2006 · 被引用 225 次 — MT1-MMP degrades extracellular matrix to make a path for cells to migrate, sheds cell surface molecules to give migratory signals, and activates ERK ( ...
由 R Ferrari 著作 · 2019 · 被引用 85 次 — Our study highlights an uncovered role for MT1-MMP in directing invadopodia assembly independent of its proteolytic activity. Electron ...
Mouse myeloma cell line NS0-derived recombinant human MMP‑14/MT1‑MMP Tyr112-Ala541 (predicted) Accession # P50281. Specificity. Detects human MMP‑14/MT1‑MMP in ...