由 HJ Guo 著作 · 2022 · 被引用 18 次 — The ubiquitin-proteasome is a well-studied pathway known to play a significant role in regulating protein homeostasis and trafficking.
Ubiquitination describes the process in which ubiquitin molecules are attached to lysine residues of a protein. The attachment of multiple ubiquitin molecules, ...
由 A Hershko 著作 · 1998 · 被引用 10563 次 — The ubiquitin system has been implicated in the immune response, development, and programmed cell death. Abnormalities in ubiquitin-mediated processes have been ...
由 RB Damgaard 著作 · 2021 · 被引用 68 次 — Ubiquitination has emerged as one of the most pervasive post-translational protein modifications. Tens-of-thousands of ubiquitination sites on ...
Ubiquitin is a small protein that exists in all eukaryotic cells. It performs its myriad functions through conjugation to a large range of target proteins. A ...
The ubiquitin (Ub) system plays a pivotal role in protein homeostasis by regulating the turnover of proteins important in a plethora of regulatory pathways such ...
由 CM Pickart 著作 · 2004 · 被引用 1912 次 — Ubiquitin is the founding member of a family of structurally conserved proteins that regulate a host of processes in eukaryotic cells. Ubiquitin and its ...