由 HJ Guo 著作 · 2023 · 被引用 26 次 — Ubiquitination (also known as ubiquitylation) is a form of post-translation modification (PTM) in which ubiquitin is attached to a target protein.
Ubiquitin's main function is to regulate protein degradation, providing an avenue for Ub to control protein expression through the UPP. The post-translational ...
由 A Hershko 著作 · 1998 · 被引用 10788 次 — The ubiquitin system has been implicated in the immune response, development, and programmed cell death. Abnormalities in ubiquitin-mediated processes have been ...
由 RB Damgaard 著作 · 2021 · 被引用 107 次 — Ubiquitination has emerged as one of the most pervasive post-translational protein modifications. Tens-of-thousands of ubiquitination sites on ...
Ubiquitin is a small (8.6 kDa) regulatory protein found in most tissues of eukaryotic organisms, i.e., it is found ubiquitously. It was discovered in 1975 ...
Ubiquitin is a protein with numerous regulatory functions in eukaryotes. Its covalent linkage as a post-translational modification to other proteins, known as ...
由 CM Pickart 著作 · 2004 · 被引用 1975 次 — Ubiquitin is the founding member of a family of structurally conserved proteins that regulate a host of processes in eukaryotic cells. Ubiquitin and its ...