telomerase

4天前—Telomerase,theenzymethatmaintainstelomeresatnaturalchromosomeends,shouldberepressedatdouble-strandbreaks(DSBs),where ...,Telomeresarespecializedstructuresattheendsofchromosomes,andtelomeraseistheenzymethatmaintainsthelengthofthetelomeres.Duringeachroundof ...,Telomerase,acellularreversetranscriptasethataddsDNAtotheendsofchromosomes,isreactivatedorupregulatedinthevastmajorityofadvanced .....

ATR blocks telomerase from converting DNA breaks into ...

4 天前 — Telomerase, the enzyme that maintains telomeres at natural chromosome ends, should be repressed at double-strand breaks (DSBs), where ...

Telomerase

Telomeres are specialized structures at the ends of chromosomes, and telomerase is the enzyme that maintains the length of the telomeres. During each round of ...

Telomerase - an overview

Telomerase, a cellular reverse transcriptase that adds DNA to the ends of chromosomes, is reactivated or upregulated in the vast majority of advanced ...

Telomerase

由 MI Zvereva 著作 · 2010 · 被引用 306 次 — Telomerase is the enzyme responsible for maintenance of the length of telomeres by addition of guanine-rich repetitive sequences. Telomerase activity is ...

TERT telomerase reverse transcriptase [ (human)]

7 天前 — Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of ...

什麼是端粒(telomere)?

2019年4月12日 — 生命體中有一種酵素叫做端粒酶(telomerase),端粒酶(telomerase)在細胞中會藉由把重複序列添加到端粒(telomere)上以維持端粒(telomere)的長度,在一般的 ...

端粒酶

端粒酶(英語:Telomerase)是一種由RNA和蛋白質組成的核糖核蛋白複合體,屬於反轉錄酶,與端粒的調控機理密切相關。人類的端粒酶亞單位基因已被複製出來,分別是端粒 ...

端粒酶

端粒酶(英语:Telomerase)是一种由RNA和蛋白质组成的核糖核蛋白复合体,属于反转录酶,与端粒的调控机理密切相关。人类的端粒酶亚单位基因已被复制出来,分别是端粒 ...

端粒酶核酸分子之生理意義及藥物開發= Telomerase RNA ...

正常人類體細胞隨著細胞持續分裂,端粒長度會逐漸縮短,當端粒短至一定程度時會啟動老化機制而使細胞處於停滯狀態,不再持續分裂生長。然而在大部分的癌細胞中、端粒酶的再 ...

首次解析出端粒酶結構! 抗老化及抗癌的新時代來臨?

2018年4月26日 — ... telomerase reverse transcriptase, TERT)、端粒酶RNA (telomerase RNA, hTR) 等基質組成的複合體。它能在染色體的末端上下移動,複製模板,進而 ...