exonuclease

Exonucleasesareenzymesthatworkbycleavingnucleotidesoneatatimefromtheend(exo)ofapolynucleotidechain.Ahydrolyzingreactionthatbreaks ...,ExonucleasesoftenactredundantlyinbiologicalfunctionsofRNAprocessinganddegradation,mutationavoidance,andinDNArepairandrecombination.Therefore ...,ExonucleaseVIIwillnotbeabletodigestcircularssDNAwhenEDTAispresentinthereaction.IntheabsenceofMg++theenzymewillactasap...

Exonuclease

Exonucleases are enzymes that work by cleaving nucleotides one at a time from the end (exo) of a polynucleotide chain. A hydrolyzing reaction that breaks ...

Exonuclease

Exonucleases often act redundantly in biological functions of RNA processing and degradation, mutation avoidance, and in DNA repair and recombination. Therefore ...

Properties of Exonucleases and Non

Exonuclease VII will not be able to digest circular ssDNA when EDTA is present in the reaction. In the absence of Mg++ the enzyme will act as a pure exonuclease ...

The role of DNA exonucleases in protecting genome ...

由 PA Mason 著作 · 2012 · 被引用 46 次 — Exonucleases are key enzymes involved in many aspects of cellular metabolism and maintenance and are essential to genome stability, acting to cleave DNA ...

Exonuclease - an overview

Exonucleases often act redundantly in biological functions of RNA processing and degradation, mutation avoidance, and in DNA repair and recombination. Therefore ...

Exonuclease I (20 UµL)

Thermo Scientific Exonuclease I (ExoI) degrades single-stranded DNA in a 3'5' direction. It releases deoxyribonucleoside 5'-monophosphates in a stepwise ...

Exonuclease III (E. coli)

Exonuclease III is a double-stranded DNA specific exonuclease that catalyzes the stepwise removal of mononucleotides from the 3'-hydroxyl termini.

The enzymatic basis of processivity in λ exonuclease

由 K Subramanian 著作 · 2003 · 被引用 174 次 — λ Exonuclease is a toroidal homotrimeric molecule and this quaternary structure is a recurring theme in proteins engaged in processive reactions in nucleic acid ...

外切酶

外切酶,或核酸外切酶(英語:exonucleases)可以是單獨存在的酶,或是大型酶複合物的一部分。此類酶能將聚核苷酸鏈分解成核苷酸。作用方式是將3'或5'端上的磷酸酯鍵 ...