It is a 15.5–16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 is part ...
IL-2 has an immunoregulatory role; it promotes the growth and development of peripheral immune cells in the initiation of the (defensive) immune response, and ...
2022年4月19日 — 1. Soluble IL2-R is a marker for T cell activation. Clinical conditions in which elevated soluble IL-2R levels are detected include autoimmune ...
由 T Jiang 著作 · 2016 · 被引用 477 次 — Interleukin-2 (IL-2) is one of the key cytokines with pleiotropic effects on immune system. It has been approved for the treatment of metastatic renal cell ...
由 SH Ross 著作 · 2018 · 被引用 684 次 — IL-2 controls CD4+ T cell fate by controlling the expression of the key cytokine receptors, transcription factors, chromatin regulators, and effector cytokines.
由 O Boyman 著作 · 2012 · 被引用 1839 次 — Under steady-state resting conditions, interleukin-2 (IL-2) is mainly produced by activated CD4+ T cells in secondary lymphoid organs.