由 RT Keenan 著作 · 2020 · 被引用 87 次 — Urate is the end-product of the purine metabolism in humans. The dominant source of urate is endogenous purines and the remainder comes through diet.
Urate is the breakdown product of purine nucleotides in humans. The major site of urate formation is the liver; however, many tissues contribute to the output.
由 D Hyndman 著作 · 2016 · 被引用 143 次 — Urate handing in the human body is a complex system including three major processes: production, renal elimination, and intestinal elimination.
In humans uric acid (actually hydrogen urate ion) is the final oxidation (breakdown) product of purine metabolism and is excreted in urine, whereas in most ...
由 WJ Tsai 著作 · 2005 — Urate as a Cause of Rapidly Progressive Nephropathy. 尿酸鹽沈積為快速進行性 ... Gouty nephropathy is usually a late manifestation of severe gouty arthritis. It is ...