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Defectiveproto-oncogenesandtumor-suppressorgenesactsimilarlyataphysiologiclevel:theypromotetheinceptionofcancerbyincreasingtumorcellnumber ...,Thisself-destructionmechanismensuresthatdamagedDNAisnotpassedontodaughtercellsandisimportantinpreventin...
Cell cycle checkpoints and their inactivation in human cancer
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由MMolinari著作·2000·被引用464次—Mutationsofcheckpointproteinsarefrequentinalltypesofcancerasdefectsincellcyclecontrolcanleadtogeneticinstability.Thisreviewwillfocuson ...
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