The Adenomatous polyposis coli (APC) protein is a component of the Wnt-β-catenin signaling pathway that negatively regulates cell growth. APC is typically found ...
APC, WNT signaling pathway regulator is a protein that in humans is encoded by the APC gene. APC. Available structures. PDB, Ortholog search: PDBe RCSB ...
APC/C regulates the cell cycle primarily through collaboration with CDC20 and CDH1. The APC/C-CDC20 complex primarily regulates the degradation of related ...
由 TC He 著作 · 1998 · 被引用 5977 次 — Here, the c-MYC oncogene is identified as a target gene in this signaling pathway. Expression of c-MYC was shown to be repressed by wild-type APC and activated ...
由 NM Al-Thani 著作 · 2022 · 被引用 2 次 — 74 known and 703 novel Wnt β-catenin pathway protein-protein interactions were recovered in this study. There were 8 known and 31 novel APC ...
由 J Schneikert 著作 · 2007 · 被引用 365 次 — APC mutations are far more frequent than β‐catenin mutations in colorectal cancer. More cellular functions related to tumour progression have been assigned to ...
Details of available pathways can be found on each course's page. Browse All Diplomas. University Pathways and Articulations. APC University Pathways and ...
