由 KG Nguyen 著作 · 2020 · 被引用 251 次 — Interleukin-12 (IL-12) is a potent, pro-inflammatory type 1 cytokine that has long been studied as a potential immunotherapy for cancer.
由 T Hamza 著作 · 2010 · 被引用 455 次 — Interleukin 12 (termed IL-12p70 and commonly designated IL-12) is an important immunoregulatory cytokine that is produced mainly by antigen-presenting cells ...
由 G Trinchieri 著作 · 2003 · 被引用 4693 次 — Interleukin-12 (IL-12) is a heterodimeric pro-inflammatory cytokine that regulates T-cell and natural killer-cell responses, induces the ...
由 J Liu 著作 · 2005 · 被引用 144 次 — Interleukin-12 (IL-12) is a heterodimeric cytokine composed of the p35 and p40 subunits. It is produced by antigen-presenting cells and plays a critical ...
由 G Haskó 著作 · 1999 · 被引用 98 次 — Interleukin-12 (IL-12) is a pivotal cytokine in driving the immune system towards a T helper (Th)1 type response and preventing a Th2 type immune profile.
IL-12 is a Th1 cytokine that is predominantly generated by cells in the innate immune system. Its role is associated with the differentiation of naïve T cells ...
Interleukin 12 (IL-12) is an interleukin that is naturally produced by dendritic cells, macrophages, neutrophils, helper T cells and human B-lymphoblastoid ...